New research published in the British journal Age and Ageing suggests that cognitive decline among older adults is not normal. In fact, two out of every three older adults experience only a trivial amount of decline in cognitive performance over a decade. The finding challenges widely held beliefs about cognitive decline and aging.
These findings have important implications for the care of seniors. Doctors and hospital staff often assume that cognitive decline is a part of normal aging, which leads to clinicians writing off poor performance from an elderly patient as something that is to be expected. With an understanding that cognitive decline is not normal, however, poor performance is more likely to be investigated. Preventable or reversible conditions, such as delirium, medication side effects, or vitamin deficiency can then be properly addressed.
The researchers were from Duke University, Rush University, and the Institute for Aging Research of Hebrew SeniorLife, an affiliate of Harvard Medical School. They analyzed data from the Religious Orders Study, a long-term study of cognitive aging and neuropathology conducted at Rush University in Chicago. More than 1000 study participants aged 56 to 102 were followed for up to 12 years, and their cognitive abilities were measured annually.
The researchers identified three groups of people: those experiencing slow, moderate and rapid cognitive decline. “This was a study of cognitive performance, not IQ,” explains Dr. Richard N. Jones, a senior scientist at the Institute for Aging Research. “But one could think of our results in terms of an outcome that was scored like an IQ test, where 100 was average and the normal range is between 70 and 130.”
Take a 75-year-old person, with a score of 100 in 2005. In 2015, they would be expected to have a score of 94 if they were in the slow decline group. “That is not much of a change, and it is the group where most people fit,” says Dr. Jones.
About one in four participants were in the moderate decline group. A 75-year-old with a score of 100 in 2005 would be expected to have a score of 75 in 2015 if they were a member of this group. If they were experiencing fast cognitive decline, a 75-year-old with a cognitive performance score of 100 in 2005 would be expected to have a score of 57 in 2015.
“People with moderate or fast cognitive decline, and their families, probably need medical or social support,” says Dr. Jones. The authors found that people in the moderate and fast decline groups had more Alzheimer’s disease neuropathology than did people in the slow decline class.
The group now hopes to find a way to identify people who have a high probability of belonging to the moderate or fast decline groups, and to try to predict what factors influence when a person might switch from a slow decline group to a moderate or fast decline group.
The researchers are grateful for the voluntary participation in the Religious Orders Study on the part of more than 1,000 nuns, priests and brothers from across the country. “Without the generosity of their gifts of time, effort and organ donation, we simply could not advance science in this or any other area of cognitive aging,” says Dr. Jones.
Source: Founded in 1903, Hebrew SeniorLife, an affiliate of Harvard Medical School, is a nonprofit, nonsectarian organization devoted to innovative research, health care, education and housing that improves the lives of seniors. For more information, please visit www.hebrewseniorlife.org.